The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

A 28-year-old woman was admitted to the hospital because of severe hypoxemia and right heart failure that had been caused by ...

A small-molecule drug proves its mettle in the treatment of spinal muscular atrophy, a disease amenable to intervention at the pre-mRNA level.

“Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry toward higher levels of integrated control by consolidated profit-seeking ...

Though infant mortality has continuously been targeted by health policy agendas, policies tend to place it in an individualistic and narrow frame, failing to consider and address its structural ...

Understanding today’s corporatization of U.S. health care requires seeing it from a historical perspective, as a process that began with a change in the business model of care delivery in the 1920s.

After a year of clinical rotations in which a medical student learns to face death up close, her experience on a silent meditation retreat provides her with new perspective on death and life.

In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone ...

During 2018–2024, the percentage of N. gonorrhoeae isolates carrying tetM, which confers tetracycline resistance, increased from less than 10% to more than 30% across the United States.

Endovascular thrombectomy has been shown to be safe and effective in selected patients with acute ischemic stroke due to large-vessel occlusion (LVO) up to 24 hours after symptom onset.1 In pivotal ...

NEJM uses highly rigorous editorial, peer, and statistical review processes to evaluate manuscripts for scientific accuracy, novelty, and importance.

Primary care physicians have been leaving traditional practices for concierge and direct primary care practices, in which patients are offered personalized and more accessible primary care in excha ...