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CD:徐瑞华/王峰团队揭示HDAC抑制剂不增效免疫疗法对抗实体瘤的原因 ...
总之,该研究发现,血管异常化是导致HDACi与ICIs联合治疗方案在实体瘤中表现不佳的重要原因,而在二联疗法的基础上引入抗血管生成治疗(三联疗法),可显著改善血管异常,并增强免疫治疗的疗效。
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