The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

A 28-year-old woman was admitted to the hospital because of severe hypoxemia and right heart failure that had been caused by ...

A small-molecule drug proves its mettle in the treatment of spinal muscular atrophy, a disease amenable to intervention at the pre-mRNA level.

The author describes the scientific foundations of a clinical trial of a first-in-class small-molecule estrogen receptor degrader to treat patients with metastatic breast cancer.

The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of ...

New data show that the United States continues to fall short when it comes to both protecting the health of individual people and promoting societal well-being.

Several barriers to access to preexposure prophylaxis for HIV could be alleviated by making it available over the counter. This step could particularly facilitate access among groups that face stigma.

Thinking of “culture” as a process in which tensions between social values are resolved, rather than as a fixed state, may help U.S. health care leaders envision an approach to transforming ...

Much of the food consumed in the United States is ultraprocessed. Evidence indicates that ultraprocessed food, as a class, has contributed to high rates of chronic diseases.

The rising tide of chronic kidney disease among patients with type 2 diabetes continues to challenge clinicians and health systems worldwide.1 Advances have been made in the management of chronic k ...

A 68-year-old man presented with unilateral ptosis. Neurologic examination revealed ptosis of the left eye after a sustained upward gaze. Myasthenia gravis was suspected, and an ice-pack test was p ...

To the Editor: In the 2IQP trial, Kudva and colleagues (May 8 issue) 1 found that in adults with insulin-treated type 2 diabetes, automated insulin delivery (AID) led to a greater reduction in ...