Cardiomyocyte YOD1 is highly expressed and promotes cardiomyocyte hypertrophy 单细胞测序显示YOD1在重构心肌细胞中高表达。 体外实验证实YOD1过表达加剧Ang II诱导的心肌细胞肥大，而敲低YOD1则产生相反效果。 Cardiomyocyte-specific knockout of YOD1 alleviated ...

B.S. in Biochemistry & Psychology, University of New Mexico, 2021 Cardiac hypertrophy is an adaptive or maladaptive response to stress caused by changes in pressure or volume, which results in an ...

GADD45A suppression contributes to cardiac remodeling by promoting inflammation, fibrosis and hypertrophy. Cellular and Molecular Life Sciences. doi.org/10.1007/s00018-025-05704-x.

When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the ...

Cardiomyocyte hypertrophy indexes (i.e., single-cell surface area, left ventricular fibrosis area, BNP levels, and β-MHC levels) were measured with hematoxylin-eosin and Masson's trichrome ...

B.A. in Chemistry, Carleton College, 2019 Some of the most severe forms of cardiovascular disease include genetic mutations affecting the proteome of cardiomyocytes through the co-transcriptional ...

NEXEL, a leader in iPSC technology, Earns the First ISO/IEC 17025:2017 for iPSC-derived Cardiomyocyte-based Cardiac Safety Testing ...