Pixel Game Maker MV is the latest option. This piece of software is currently in Early Access but allows for gerenating assets, animating sprites, giving objects actions and connecting levels ...

The makers of Sonic Superstars think pixel art is going to become an even bigger niche in the future, even for indie developers.

Studio PICO, a two-man developer based in Japan, is currently in the early stages of development on Grand Exile, a pixel art 2D action and shooting game hybrid planned for release on Switch and PC.