You can use Nuitka to compile Python programs to standalone executables, then redistribute them without the Python runtime.

The Transcrypt Python to JavaScript compiler is a relatively new open source project, aiming at executing Python 3.6 at JavaScript speed, with comparable file sizes.

Dropbox's compiler for Python uses the LLVM to push the language closer to C/C++ speeds, but it's far from production-ready Fast development or fast execution, take your pick. Python programmers ...