Voltage-gated sodium channels (VGSCs) are responsible for transmembrane (TM) sodium ion conduction and, in eukaryotes, for electrical signalling in excitable cells 1. In humans, mutations in different ...

Most natural proteins performing sophisticated tasks contain multiple domains where an active site is located at the domain interface. Comparative structural analyses suggest that major leaps in ...

Transactions of the American Mathematical Society, Vol. 159 (Sep., 1971), pp. 335-353 (19 pages) A ring of continuous functions is a ring of the form $C(X)$, the ring ...