Chicago Med star Kelley Mack passed away on August 2, 2025, as confirmed by a statement shared on her Instagram account by her sister on August 5. She had just turned 33 in July.

At the time of her death, the Ohio-born actor had been actively promoting the independent sci-fi feature "Universal," in which she has a starring role.

American actress Kelley Mack died on August 2, 2025, in her hometown of Cincinnati after battling glioma of the central nervous system. A year before her death, she had shared a health update.